USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q05639 USC-OGP 2-DE database:  Q05639 Q05639 General information about the entry View entry in simple text format Entry name EF1A2_HUMAN Primary accession number Q05639 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Elongation factor 1-alpha 2; Short=EF-1-alpha-2; AltName: Full=Eukaryotic elongation factor 1 A-2; Short=eEF1A-2; AltName: Full=Statin-S1;. Gene name Name=EEF1A2 Synonyms=EEF1AL, STN Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1143: pI=6.86; Mw=59744 SPOT OGP-1167: pI=6.89; Mw=47770 Cross-references UniProtKB/Swiss-Prot Q05639; EF1A2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name EF1A2_HUMAN Primary accession number Q05639 Secondary accession number(s) B5BUF3 E1P5J1 P54266 Q0VGC7 Sequence was last modified on  June 1, 1994 (version 1) Annotations were last modified on  March 15, 2017 (version 183) Name and origin of the protein Description RecName: Full=Elongation factor 1-alpha 2; Short=EF-1-alpha-2; AltName: Full=Eukaryotic elongation factor 1 A-2; Short=eEF1A-2; AltName: Full=Statin-S1; Gene name Name=EEF1A2 Synonyms=EEF1AL, STN Encoded on Name=EEF1A2; Synonyms=EEF1AL, STN Keywords 3D-structure; Acetylation; Autism spectrum disorder; Complete proteome; Disease mutation; Elongation factor; Epilepsy; GTP-binding; Mental retardation; Methylation; Nucleotide-binding; Nucleus; Phosphoprotein; Polymorphism; Protein biosynthesis; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X70940; CAA50280.1; -; mRNA EMBL AF163763; AAF80488.1; -; Genomic_DNA EMBL AB451389; BAG70203.1; -; mRNA EMBL AL121829; CAC15522.1; -; Genomic_DNA EMBL CH471077; EAW75260.1; -; Genomic_DNA EMBL BC000432; AAH00432.1; -; mRNA EMBL BC110409; AAI10410.1; -; mRNA EMBL L10340; AAA91835.1; -; mRNA CCDS CCDS13522.1; -; . PIR S35033; EFHUA2; . RefSeq NP_001949.1; NM_001958.3; . UniGene Hs.433839; -; . PDB 3C5J; X-ray; 1.80 A; C=343-355 PDBsum 3C5J; -; . ProteinModelPortal Q05639; -; . SMR Q05639; -; . BioGrid 108238; 124; . DIP DIP-40060N; -; . IntAct Q05639; 29; . MINT MINT-1141378; -; . STRING 9606.ENSP00000217182; -; . BindingDB Q05639; -; . ChEMBL CHEMBL1795122; -; . iPTMnet Q05639; -; . PhosphoSitePlus Q05639; -; . SwissPalm Q05639; -; . BioMuta EEF1A2; -; . DMDM 544231; -; . EPD Q05639; -; . MaxQB Q05639; -; . PaxDb Q05639; -; . PeptideAtlas Q05639; -; . PRIDE Q05639; -; . TopDownProteomics Q05639; -; . DNASU 1917; -; . Ensembl ENST00000217182; ENSP00000217182; ENSG00000101210; . Ensembl ENST00000298049; ENSP00000298049; ENSG00000101210; . GeneID 1917; -; . KEGG hsa:1917; -; . UCSC uc002yfe.3; human; . CTD 1917; -; . DisGeNET 1917; -; . GeneCards EEF1A2; -; . HGNC HGNC:3192; EEF1A2; . HPA CAB034019; -; . HPA HPA051759; -; . HPA HPA053862; -; . HPA HPA056990; -; . MalaCards EEF1A2; -; . MIM 602959; gene; . MIM 616393; phenotype; . MIM 616409; phenotype; . neXtProt NX_Q05639; -; . OpenTargets ENSG00000101210; -; . PharmGKB PA36219; -; . eggNOG KOG0052; Eukaryota; . eggNOG COG5256; LUCA; . GeneTree ENSGT00670000097815; -; . HOGENOM HOG000229291; -; . HOVERGEN HBG000179; -; . InParanoid Q05639; -; . KO K03231; -; . OMA VACTFES; -; . OrthoDB EOG091G05LW; -; . PhylomeDB Q05639; -; . TreeFam TF300304; -; . Reactome R-HSA-156842; Eukaryotic Translation Elongation; . ChiTaRS EEF1A2; human; . EvolutionaryTrace Q05639; -; . GeneWiki EEF1A2; -; . GenomeRNAi 1917; -; . PRO PR:Q05639; -; . Proteomes UP000005640; Chromosome 20; . Bgee ENSG00000101210; -; . CleanEx HS_EEF1A2; -; . Genevisible Q05639; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0098574; C:cytoplasmic side of lysosomal membrane; NAS:ParkinsonsUK-UCL; . GO GO:0005853; C:eukaryotic translation elongation factor 1 complex; IEA:Ensembl; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0043025; C:neuronal cell body; IEA:Ensembl; . GO GO:0005525; F:GTP binding; IEA:UniProtKB-KW; . GO GO:0003924; F:GTPase activity; IBA:GO_Central; . GO GO:0019901; F:protein kinase binding; IPI:UniProtKB; . GO GO:0003746; F:translation elongation factor activity; IBA:GO_Central; . GO GO:0008135; F:translation factor activity; RNA binding; NAS:ProtInc GO GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl; . GO GO:0090218; P:positive regulation of lipid kinase activity; IDA:UniProtKB; . GO GO:1904714; P:regulation of chaperone-mediated autophagy; NAS:ParkinsonsUK-UCL; . GO GO:0051602; P:response to electrical stimulus; IEA:Ensembl; . GO GO:0010035; P:response to inorganic substance; IEA:Ensembl; . Gene3D 3.40.50.300; -; 1; . HAMAP MF_00118_A; EF_Tu_A; 1; . InterPro IPR004161; EFTu-like_2; . InterPro IPR031157; G_TR_CS; . InterPro IPR027417; P-loop_NTPase; . InterPro IPR000795; TF_GTP-bd_dom; . InterPro IPR009000; Transl_B-barrel; . InterPro IPR009001; Transl_elong_EF1A/Init_IF2_C; . InterPro IPR004539; Transl_elong_EF1A_euk/arc; . InterPro IPR004160; Transl_elong_EFTu/EF1A_C; . Pfam PF03144; GTP_EFTU_D2; 1; . Pfam PF03143; GTP_EFTU_D3; 1; . PRINTS PR00315; ELONGATNFCT; . SUPFAM SSF50447; SSF50447; 1; . SUPFAM SSF50465; SSF50465; 1; . SUPFAM SSF52540; SSF52540; 1; . TIGRFAMs TIGR00483; EF-1_alpha; 1; . PROSITE PS00301; G_TR_1; 1; . PROSITE PS51722; G_TR_2; 1; .

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